Related Experiment Video
Updated: Jun 30, 2026
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Posttraumatic cellulitis and ulcerative conjunctivitis caused by Yersinia enterocolitica O:8
1Ophthalmic Plastic Surgery, Albany Medical Center, Lions Eye Institute, Albany, New York 12159, USA. davidmills4186@msn.com
Ophthalmic Plastic and Reconstructive Surgery
|September 23, 2008
Summary
This case report details a rare instance of orbital cellulitis caused by Yersinia enterocolitica O:8. Prompt antibiotic treatment resolved the infection, highlighting the importance of considering infectious causes in orbital inflammation.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Orbital cellulitis is a serious condition often associated with bacterial infection following trauma.
- Intraorbital foreign bodies are a common concern in patients presenting with orbital trauma and inflammation.
Observation:
- A 55-year-old male presented with orbital cellulitis and suspected foreign body post-ocular trauma.
- Surgical exploration revealed no foreign body, but cultures identified Yersinia enterocolitica O:8.
Findings:
- The patient's orbital cellulitis resolved with intravenous antibiotics.
- This is the first reported case of human orbital cellulitis attributed to Yersinia enterocolitica O:8.
Implications:
- Orbital cellulitis can be caused by unusual pathogens like Yersinia enterocolitica.
- The clinical presentation, including conjunctival ulcerations, may mimic a foreign body, necessitating a broad differential diagnosis.
Related Concept Videos
01:22Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
01:18Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
01:24Plague
Plague is a highly virulent zoonotic disease caused by Yersinia pestis, a Gram-negative, facultatively anaerobic coccobacillus. This pathogen primarily circulates among rodent populations and is transmitted to humans through the bite of infected fleas. Additional transmission routes include direct contact with infected animal tissue or inhalation of respiratory droplets from individuals with pneumonic plague. These multiple transmission pathways highlight the bacterium’s potential for rapid...
01:26Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
01:27Acute Pyelonephritis I: Introduction
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...