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Published on: September 5, 2017
Annual risk of tuberculosis infection in Chennai city
P G Gopi1, V Venkatesh Prasad, M Vasantha
1Tuberculosis Research Centre, Mayor V.R. Ramanathan Road, Chetput, Chennai-600 031.
Insights
Tuberculosis infection risk in Chennai children is higher in urban settings, with slum areas showing a slightly elevated prevalence. This study provides crucial baseline data for monitoring future tuberculosis trends in the city.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Tuberculosis (TB) remains a significant global health challenge.
- Understanding the prevalence of Mycobacterium Tuberculosis infection in urban pediatric populations is crucial for targeted interventions.
Purpose of the Study:
- To determine the proportion of children infected with Mycobacterium Tuberculosis in Chennai city.
- To establish baseline data for monitoring TB epidemiological trends in Chennai.
Main Methods:
- Cluster sampling methodology used to select approximately 7000 children aged 1-9 years.
- Mantoux test administered to 7098 children, with data stratified by slum and non-slum areas.
- Analysis of infection prevalence considering BCG scar status.
Main Results:
- Overall prevalence of infection was 10.5% (ARTI 2.0%) among children without BCG scars.
- Prevalence was higher in slum areas (11.1%; ARTI 2.1%) compared to non-slum areas (8.9%; ARTI 1.7%), though not statistically significant.
- Infection prevalence was similar irrespective of BCG scar status.
Conclusions:
- The risk of tuberculosis infection in Chennai is higher in urban areas compared to rural settings.
- Findings are comparable to previous studies in other cities, highlighting the urban TB burden.
- The data serves as essential baseline information for future epidemiological trend monitoring in Chennai.
Aim:
To study the proportion of children infected with Mycobacterium Tuberculosis in Chennai city.
Methodology:
A cluster sampling methodology was adopted to select an estimated sample size of 7000 children from five corporation zones selected systematically from ten zones of the city. A total of 7098 children aged 1-9 years were subjected to Mantoux and test read; 1897 (27%) from slum area and 5201 (73%) from non-slum area.
Results:
The prevalence of infection among children without BCG scar was estimated to be 10.5 % (ARTI of 2.0%) and was similar to that among children irrespective of scar status. The prevalence of infection was higher among children in slum areas (11.1%; ARTI 2.1%) compared to non-slum areas (8.9%; ARTI 1.7%); but the difference was not statistically different.
Conclusion:
The tuberculosis situation in Chennai as measured by risk of infection was higher in urban city area than rural areas and comparable to that found in other cities as reported from earlier studies. This information can be used as baseline information for monitoring the epidemiological trends in Chennai city in future.
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