Annual risk of tuberculosis infection in Chennai city

P G Gopi1, V Venkatesh Prasad, M Vasantha

  • 1Tuberculosis Research Centre, Mayor V.R. Ramanathan Road, Chetput, Chennai-600 031.

Insights

Tuberculosis infection risk in Chennai children is higher in urban settings, with slum areas showing a slightly elevated prevalence. This study provides crucial baseline data for monitoring future tuberculosis trends in the city.

Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • Tuberculosis (TB) remains a significant global health challenge.
  • Understanding the prevalence of Mycobacterium Tuberculosis infection in urban pediatric populations is crucial for targeted interventions.

Purpose of the Study:

  • To determine the proportion of children infected with Mycobacterium Tuberculosis in Chennai city.
  • To establish baseline data for monitoring TB epidemiological trends in Chennai.

Main Methods:

  • Cluster sampling methodology used to select approximately 7000 children aged 1-9 years.
  • Mantoux test administered to 7098 children, with data stratified by slum and non-slum areas.
  • Analysis of infection prevalence considering BCG scar status.

Main Results:

  • Overall prevalence of infection was 10.5% (ARTI 2.0%) among children without BCG scars.
  • Prevalence was higher in slum areas (11.1%; ARTI 2.1%) compared to non-slum areas (8.9%; ARTI 1.7%), though not statistically significant.
  • Infection prevalence was similar irrespective of BCG scar status.

Conclusions:

  • The risk of tuberculosis infection in Chennai is higher in urban areas compared to rural settings.
  • Findings are comparable to previous studies in other cities, highlighting the urban TB burden.
  • The data serves as essential baseline information for future epidemiological trend monitoring in Chennai.
Abstract

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