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Updated: Jun 30, 2026

Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats
Published on: March 28, 2025
[Hydrocephalus as initial presentation of a spinal cord tumour in a child]
Louise Møller Jørgensen1, Karsten Nysom, Lene Daugaard Lavard
1Glostrup Hospital, Neurokirurgisk Afdeling, Glostrup. LMJ@mail.tele.dk
Insights
A previously healthy child developed a spinal cord tumor after initial symptoms of increased intracranial pressure and hydrocephalus. This case highlights the importance of considering spinal cord tumors in pediatric patients with unexplained neurological signs.
Area of Science:
- Pediatric Neurology
- Neuro-oncology
- Neurosurgery
Background:
- Increased intracranial pressure (ICP) and hydrocephalus in children can have various etiologies.
- Early diagnosis and intervention are crucial for favorable outcomes.
Observation:
- A two-year-old girl presented with vomiting, lethargy, and an unstable gait, indicative of increased ICP.
- Communicating hydrocephalus was diagnosed, and a ventriculoperitoneal shunt was surgically placed.
Findings:
- Two years post-shunt placement, the patient developed myelopathy signs.
- A spinal cord tumor, located between thoracic levels 3 and 9, was subsequently diagnosed.
Implications:
- Spinal cord tumors should be considered in the differential diagnosis of pediatric hydrocephalus and increased ICP of unknown origin.
- This case underscores the need for thorough neurological evaluation in children presenting with atypical neurological symptoms.
Abstract:
We report a previously healthy two-year-old girl who initially presented with signs of increased intracranial pressure of vomiting, lethargy and unstable gait. She had communicating hydrocephalus and a ventriculoperitoneal shunt was placed. Two years later the girl developed signs of myelopathy and was diagnosed with a spinal cord tumour between Th3 and Th9. We suggest that spinal cord tumour should be considered in patients with increased intracranial pressure or hydrocephalus of unknown origin.
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Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
