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Published on: February 6, 2020
Migratory polyarthritis as a paraneoplastic syndrome
Melanie Zupancic1, Ani Annamalai, Jennifer Brenneman
1Department of Internal Medicine, Division of Internal Medicine/Psychiatry, Southern Illinois University School of Medicine, Springfield, IL 62794, USA. mzupancic@siumed.edu
Carcinomatous polyarthritis (CP), a rare cancer complication, often mimics other joint conditions and signals an underlying malignancy. Early recognition and treatment of the primary cancer are crucial for managing CP.
Area of Science:
- Rheumatology
- Oncology
- Paraneoplastic Syndromes
Background:
- Carcinomatous polyarthritis (CP) is a rare paraneoplastic syndrome linked to various solid tumors.
- It often presents before the primary cancer is detected, necessitating prompt recognition.
Observation:
- A case of a patient presenting with asymmetric inflammatory polyarthritis is detailed.
- This patient was subsequently diagnosed with bronchogenic carcinoma.
Findings:
- CP's presentation can mimic other polyarticular disorders, complicating diagnosis.
- Effective management of CP relies on treating the underlying neoplastic disease.
Implications:
- Highlights the importance of considering CP in the differential diagnosis of inflammatory polyarthritis.
- Emphasizes the need for a thorough diagnostic approach to identify underlying malignancies.
- Provides insights into the pathophysiology and management strategies for CP.
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