Sleep disorders and end-stage renal disease
1Sleep Centre, Foothills Medical Centre, Calgary, Alberta, Canada. phanly@ucalgary.ca
Current Opinion in Pulmonary Medicine
|September 25, 2008
Summary
Sleep disorders are common in patients with end-stage renal disease (ESRD), impacting quality of life and increasing cardiovascular mortality. Cognitive-behavioral therapy may improve sleep quality and reduce hypnotic medication use in ESRD patients.
Area of Science:
- Nephrology
- Sleep Medicine
- Cardiovascular Health
Background:
- Sleep disorders are prevalent in patients with end-stage renal disease (ESRD).
- Poor sleep quality is often underrecognized in ESRD patients.
- Sleep disturbances negatively affect quality of life and are linked to increased cardiovascular mortality.
Purpose of the Study:
- To update on the prevalence and clinical significance of sleep disorders in ESRD.
- To review recent findings on the pathogenesis and treatment of these disorders.
Main Methods:
- Review of current literature on sleep disorders in ESRD.
- Analysis of recent findings on pathogenesis and treatment.
Main Results:
- Poor sleep quality is common and associated with adverse outcomes in ESRD.
- Cognitive-behavioral therapy shows promise for improving sleep and reducing medication reliance.
- Sleep apnea in ESRD involves increased chemosensitivity and upper airway narrowing.
- Renal transplantation may not fully resolve sleep apnea.
Conclusions:
- Sleep disorders are a significant issue in ESRD patients.
- Further research is needed to fully understand the clinical impact of sleep disorders in this population.
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