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Updated: Jun 30, 2026

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
[Combination therapy in patients with pulmonary arterial hypertension]
R Ewert1, C F Opitz, C Schäper
1Bereich Pneumologie/Infektiologie, Klinik und Poliklinik für Innere Medizin B, Universität Greifswald. ewert@uni-greifswald.de
Abstract:
Despite recent remarkable efforts in the medical treatment options of patients with pulmonary arterial hypertension (PAH) a considerable number of patients need escalations to improve disease related symptoms and pulmonary hemodynamics. Most of the pulmonary vascular vasodilators have been approved in its potency as an initial and sole medical option. However, there is increasing scientific evidence on the reliability, safety and effectiveness of possible combinations. This paper reviews the current scientific literature about medical escalations and combination therapy in patients with PAH.
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