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Updated: Jun 30, 2026

Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion
Published on: April 19, 2024
Long-term outcome after severe traumatic brain injury: the McGill interdisciplinary prospective study
Elaine deGuise1, Joanne leBlanc, Mitra Feyz
1Montreal General Hospital, McGill University Health Center, Montreal, Québec, Canada.
Objective:
To obtain a comprehensive understanding of long-term outcome after severe traumatic brain injury (sTBI).
Participants:
Forty-six patients with sTBI.
Design:
Comparison of interdisciplinary evaluation results at discharge from acute care and at 2 to 5 year follow-up.
Main Measures:
Extended Glasgow Outcome Scale, the FIM instrument, and the Neurobehavioral Rating Scale-Revised.
Results:
Significant improvement was observed on the FIM instrument, the Extended Glasgow Outcome Scale, and on 3 factors of the Neurobehavioral Rating Scale-Revised. These measures at discharge were significant predictors of outcome.
Conclusion:
Patients with sTBI 2 to 5 years postinjury showed relatively good physical and functional outcome but poorer cognitive and emotional outcome.
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