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A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
The computerized tomography scans and their dosimetric safety.
Ioannis Iakovou1, Niovi Karavida, Maria Kotzassarlidou
13rd Nuclear Medicine Department, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece. iiakovou@auth.gr
Computed tomography (CT) use is rising, increasing radiation exposure concerns. Minimizing radiation dose and optimizing CT referrals are crucial for patient safety and public health.
Area of Science:
- Radiology and Medical Imaging
- Radiation Oncology
- Public Health
Background:
- Increased utilization of computed tomography (CT) for diagnostics, particularly in pediatrics and asymptomatic adult screening.
- Technological advancements in CT equipment have enhanced its popularity and accessibility.
- Growing concern among physicians regarding iatrogenic malignancy risks associated with diagnostic radiation exposure.
Discussion:
- No safe radiation threshold exists; all radiation exposure carries a cancer risk, though typically smaller than natural sources.
- Widespread CT screening, especially with uncertain benefits, poses a public health concern due to cumulative radiation dose.
- The principle of 'as low as reasonably achievable' (ALARA) for radiation dose reduction is paramount.
Key Insights:
- Individualized scanner parameter adjustments are essential for minimizing radiation dose in CT procedures.
- Eliminating inappropriate CT referrals and considering alternative imaging modalities like sonography, MRI, or nuclear medicine is critical.
- Re-evaluating CT scan indications, especially for pediatric and asymptomatic populations, is necessary.
Outlook:
- Prudent and optimized use of CT remains vital for effective medical diagnosis in both children and adults.
- Physicians should adopt a case-by-case assessment for CT scan necessity.
- Continued vigilance and evidence-based practice are required to balance CT benefits against radiation risks.
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