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[Pregnancy and inflammatory myopathies]
Dalia Dimitri1, Christian Pagnoux
1Service d'Histologie, Centre de Référence des Maladies Neuromusculaires, Garches-Necker-Mondor-Hendaye, INSERM U841, CHU Henri Mondor, Assistance Publique-Hôpitaux de Paris, Créteil, France. dalia.dimitri@hmn.aphp.fr
In general, pregnancies in women with inflammatory myopathy (IM) in sustained remission have a favourable outcome, whereas those pregnant patients with active IM have an increased risk for foetal loss, intra-uterine growth retardation and/or prematurity. The effect of pregnancy on disease activity is variable. All patients with active IM need to be followed by a multidisciplinary team including obstetricians, rheumatologists and/or internists in close relationship with a neonatal intensive care unit. Maternal disease should be treated with corticosteroids, using the same dosage and regimen as for non-pregnant women and according to the disease activity and severity.
In general, pregnancies in women with inflammatory myopathy (IM) in sustained remission have a favourable outcome, whereas those pregnant patients with active IM have an increased risk for foetal loss, intra-uterine growth retardation and/or prematurity. The effect of pregnancy on disease activity is variable. All patients with active IM need to be followed by a multidisciplinary team including obstetricians, rheumatologists and/or internists in close relationship with a neonatal intensive care unit. Maternal disease should be treated with corticosteroids, using the same dosage and regimen as for non-pregnant women and according to the disease activity and severity.
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