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[Pregnancy and inflammatory myopathies].
Dalia Dimitri1, Christian Pagnoux
1Service d'Histologie, Centre de Référence des Maladies Neuromusculaires, Garches-Necker-Mondor-Hendaye, INSERM U841, CHU Henri Mondor, Assistance Publique-Hôpitaux de Paris, Créteil, France. dalia.dimitri@hmn.aphp.fr
Presse Medicale (Paris, France : 1983)
|September 27, 2008
Summary
Pregnancies in women with inflammatory myopathy (IM) generally have good outcomes if the disease is in remission. Active IM during pregnancy increases risks for fetal loss and premature birth, requiring multidisciplinary care.
Area of Science:
- Rheumatology
- Obstetrics
- Neonatology
Context:
- Pregnancy in women diagnosed with inflammatory myopathy (IM) presents unique challenges.
- Disease activity during pregnancy significantly impacts maternal and fetal outcomes.
- Management requires a coordinated approach involving multiple medical specialties.
Purpose:
- To summarize the outcomes of pregnancies in women with inflammatory myopathy.
- To highlight the risks associated with active maternal disease.
- To outline recommended management strategies for pregnant patients with IM.
Summary:
- Women with inflammatory myopathy (IM) in sustained remission typically experience favorable pregnancy outcomes.
- Active IM during pregnancy is associated with increased risks, including fetal loss, intrauterine growth retardation, and prematurity.
- Pregnancy's effect on IM activity varies, necessitating close monitoring.
Impact:
- Emphasizes the need for a multidisciplinary team approach for pregnant women with active IM, including obstetricians, rheumatologists, and neonatologists.
- Recommends corticosteroid treatment for active maternal IM, mirroring non-pregnant patient protocols.
- Informs clinical practice regarding risk assessment and management for IM patients planning pregnancy.
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