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Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
DNA as a Genetic Template02:05

DNA as a Genetic Template

Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
Complementary DNA01:44

Complementary DNA

Overview
Complementary DNA01:44

Complementary DNA

Overview
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
The Replisome03:01

The Replisome

DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...

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Related Experiment Video

Updated: Jun 30, 2026

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

Assembling materials with DNA as the guide.

Faisal A Aldaye1, Alison L Palmer, Hanadi F Sleiman

  • 1Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 2K6, Canada.

Science (New York, N.Y.)
|September 27, 2008
PubMed
Summary
This summary is machine-generated.

DNA nanotechnology uses DNA's unique properties to create precise nanoscale patterns. These DNA nanostructures precisely position functional components and serve as templates for advanced materials and biological applications.

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Last Updated: Jun 30, 2026

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
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Published on: December 1, 2017

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Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

Area of Science:

  • Biomaterials engineering
  • Nanotechnology
  • Molecular engineering

Background:

  • DNA possesses unique molecular recognition and structural properties ideal for nanoscale templating.
  • DNA nanotechnology repurposes DNA, disregarding its biological function, to engineer nanostructures.

Purpose of the Study:

  • To explore the potential of DNA as a template for nanoscale material patterning.
  • To highlight the versatility of DNA nanostructures in positioning functional components and enabling novel applications.

Main Methods:

  • Utilizing DNA's inherent coding and structural features to design and assemble addressable nanostructures.
  • Employing these DNA nanostructures to precisely position various functional elements like proteins and nanoparticles.

Main Results:

  • Demonstrated the creation of 1D, 2D, and 3D nanostructures using DNA as a template.
  • Showcased the precise positioning of proteins, nanoparticles, and transition metals within designed patterns.
  • Highlighted applications in nanowire growth, protein structural determination, and genomics platforms.

Conclusions:

  • DNA nanotechnology offers a powerful platform for nanoscale material design and fabrication.
  • The field holds significant promise for advancing both materials science and biological research through precise molecular patterning.