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[Qualitative and quantitative analysis of urolithiasis with the Rietveld method (x-ray diffraction)].

H Euler¹, H P Bastian, P J Bastian

¹Kristallograph - Mineraloge, An den Obstgärten 30, 53343, Wachtberg, Deutschland. hj.euler@t-online.de

Der Urologe. Ausg. A

|September 27, 2008

Summary

This summary is machine-generated.

The Rietveld method enables precise, standard-free crystallographic analysis of urinary stones. This innovative X-ray diffraction technique accurately quantifies stone components, aiding in detecting changes and guiding therapy.

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Area of Science:

Crystallography
Materials Science
Analytical Chemistry

Background:

The Rietveld method is a key innovation in X-ray diffraction analysis.
It has been newly applied to standard-free quantitative crystallographic analysis of urinary stones.

Purpose of the Study:

To demonstrate the capability of the Rietveld method for precise quantitative phase analysis of urinary stones.
To evaluate its accuracy in determining the composition of complex urinary stone mixtures.

Main Methods:

Application of the Rietveld method, a quantitative phase analysis technique.
Analysis of a synthetic mixture containing five common urinary stone components (whewellite, hydroxylapatite, brushite, struvite, uric acid) at 20% each by weight.

Main Results:

The Rietveld method achieved a mean absolute error of 1.6% for weight fractions of urinary stone components.
The highest error was 2.3% for hydroxylapatite, attributed to its poor crystallinity.

Conclusions:

X-ray diffraction combined with Rietveld refinement is the preferred method for qualitative and quantitative phase analysis of urinary stones.
This approach allows precise detection of changes in weight fractions for recurrent stones, informing therapeutic decisions.