Related Experiment Video
Updated: Jun 30, 2026

Biomarker Identification for Gender Specificity of Alzheimer's Disease Based on the Glial Transcriptome Profiles
Published on: May 20, 2024
Biomarkers by gender
1Institute of Gerontology, King's College London, 6th floor, Strand, London WC2R 2LS, UK; University College London Hospital Eye Department, 235 Euston Road, London NW1 2BU, UK.
Abstract:
Regressions were determined for age-related human biological functions containing information for both genders. Their intercept T(0) on the age axis (x) was used as a measure of the aging rate. The peak of the frequency distribution of T(0) was consistent with earlier estimates. The frequency distribution of the ratio R of T(0)(women)/T(0)(men) peaked at unity. However, when the T(0)-values were divided into two groups, namely those relating to functions involving musculature vs. the rest, respectively, the ratio of R for musculature was <1 and that for the latter significantly >1. This suggests that men are the stronger gender when musculature is involved, but, more broadly, women are "biologically stronger".
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