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Updated: Jun 30, 2026

Preparation of Small RNA Libraries for Sequencing from Early Mouse Embryos
Published on: October 9, 2020
MicroRNAs in embryonic stem cells
Yulei Wang1, David N Keys, Janice K Au-Young
1Gene Expression and Genotyping Assays R&D, Molecular Cell Biology Division, Applied Biosystems, Foster City, California, USA.
Abstract:
The unique properties of embryonic stem cells (ESCs) to self-renew indefinitely or to differentiate to any cell type have great potential for clinical applications in regenerative medicine. MicroRNAs (miRNAs) are emerging as important regulators of post-transcriptional gene expression and have been implicated as crucial elements in regulating ESCs. Here, we review recent progresses in characterizing the role of miRNAs in the maintenance and development of ESCs.
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