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Updated: Jun 30, 2026

Bilayer Microfluidic Device for Combinatorial Plug Production
Published on: December 1, 2023
Microfluidic production of droplet pairs
Lucas Frenz1, Joshua Blouwolff, Andrew D Griffiths
1Institut de Science et d'Ingenierie Supramoleculaires (ISIS), Universite Louis Pasteur, CNRS UMR 7006, Strasbourg, France.
Abstract:
We study a microfluidic dual nozzle for the production of water-in-oil droplet pairs. Droplets are paired by the hydrodynamic coupling of two nozzles over a wide range of aqueous and oil flow rates provided that they are larger than the channel dimensions. The droplet production frequencies and volumes are related to the flow rates through a single, experimentally determined power-law. The data are in good agreement with a model based on a geometrical decomposition of the dual nozzle leading to a general equation of droplet frequencies as a function of the various flow rates.

