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Is there a role for Helicobacter pylori infection in urological diseases?

Mohammed S Al-Marhoon1

  • 1Department of Urology, Mansoura University, Urology and Nephrology Center, Mansoura, Egypt. almarhoon@hotmail.com

Urology Journal
|October 1, 2008
PubMed

Insights

Helicobacter pylori (H pylori) infection is linked to urological conditions like bladder lymphoma and potentially prostate cancer. Further research into H pylori

Area of Science:

  • Urology
  • Gastroenterology
  • Oncology

Background:

  • Helicobacter pylori (H pylori) infection is increasingly recognized for causing both gastrointestinal and extra-intestinal disorders.
  • The bacterium's potential impact on urological health is an emerging area of research.

Purpose of the Study:

  • To investigate the association between Helicobacter pylori infection and various urological diseases.
  • To provide urologists with updated information on this subject.

Main Methods:

  • A comprehensive literature search was conducted using Medline and PubMed databases.
  • The search covered publications from 1950 to December 2007.
  • Keywords included 'Helicobacter pylori' combined with terms related to urology and specific urological conditions.

Main Results:

  • Evidence suggests a link between H pylori infection and urological diseases.
  • H pylori infection is implicated in the development of chronic cystitis, potentially leading to bladder lymphoma.
  • Epidemiological studies indicate a significant association between chronic prostatitis and prostate cancer.

Conclusions:

  • A hypothetical model is proposed to link H pylori infection to prostate and bladder diseases.
  • Further collaborative research between urologists and scientists is needed to explore this underinvestigated field.
  • Eradication of H pylori may offer a preventive strategy for bladder and prostate cancers, similar to its role in treating peptic ulcer disease and gastric cancer.
Abstract

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