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Published on: August 12, 2019
Total syntheses of (+/-)-montanin A and (+/-)-teuscorolide
I-Chia Chen1, Yen-Ku Wu, Hsing-Jang Liu
1Department of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Abstract:
The first total syntheses of (+/-)-montanin A and (+/-)-teuscorolide have been achieved from an advanced precursor previously developed via a Diels-Alder strategy; in the synthetic sequence, the synthesis of montanin A was first accomplished in 8 steps, from which teuscorolide was readily achieved in 2 steps by using a novel furan oxidative cyclization-retro-cyclization process as a key operation.

