A novel method for the synthesis of substituted 3,4-dihydrocoumarin derivatives via isocyanide-based three-component
Ahmad Shaabani1, Afshin Sarvary, Ebrahim Soleimani
1Department of Chemistry, Shahid Beheshti University, P. O. Box 19396-4716, Tehran, Iran. a-shaabani@cc.sbu.ac.ir
Abstract:
A new one-pot procedure for the efficient synthesis of novel 3,4-dihydrocoumarin derivatives using commercially available substituted 2-hydroxybenzaldehydes, Meldrum's acid, and isocyanides by a three-component condensation reaction in dichloromethane at room temperature without using any catalysts and activation was developed.
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