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An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Central venous catheter-associated infections.
Walter Zingg1, Vanessa Cartier-Fässler, Bernhard Walder
1Doctor Infection Control Program, Geneva University Hospitals, 24 Rue Micheli-du-Crest, 1211 Geneva, Switzerland. walter.zingg@hcuge.ch
Best Practice & Research. Clinical Anaesthesiology
|October 4, 2008
Summary
Non-cuffed central venous catheters (CVCs) are common in hospitals but carry a high risk of catheter-associated bloodstream infections (CRBSI). This review details CRBSI risks, definitions, diagnostics, and prevention for these CVCs.
Area of Science:
- Infectious Diseases
- Medical Devices
- Hospital Epidemiology
Background:
- Vascular access devices are crucial for hospitalized patients.
- Non-cuffed central venous catheters (CVCs) are frequently used but pose significant infection risks.
- Catheter-associated bloodstream infections (CRBSI) are a major concern with CVCs.
Purpose of the Study:
- To review the epidemiology and risk of CRBSI associated with non-cuffed CVCs.
- To provide accepted definitions and diagnostic techniques for CRBSI.
- To highlight effective prevention strategies for CRBSI in non-cuffed CVCs.
Main Methods:
- Literature review focusing on non-cuffed CVCs and CRBSI.
- Analysis of epidemiological data and incidence densities.
- Compilation of diagnostic criteria and prevention measures.
Main Results:
- Non-cuffed CVCs are the most common catheter type after peripheral lines.
- CRBSI incidence density ranges from 2 to 7 episodes per 1000 catheter-days.
- Risk varies by ward, institution, and region.
Conclusions:
- Non-cuffed CVCs present a substantial risk for CRBSI.
- Standardized definitions, diagnostics, and prevention are essential.
- Effective management strategies can mitigate CRBSI risks.
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