Related Experiment Video
Updated: Jun 29, 2026

05:05
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Retrieval of a mispositioned Ex-PRESS glaucoma device
M Sinan Saricaoglu1, Ahmet Karakurt, O Faruk Recep
1From Ankara Numune Training and Research Hospital, Third Eye Clinic, Ankara, Turkey.
Summary
A dislocated Ex-PRESS glaucoma drainage device in pseudoexfoliative glaucoma was removed. Trabeculectomy successfully relieved intraocular pressure, suggesting it as a viable treatment for failed glaucoma devices.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Surgical Innovation
Background:
- Pseudoexfoliative glaucoma presents unique challenges for intraocular pressure management.
- Glaucoma drainage devices, like the Ex-PRESS device, are used to lower eye pressure.
- Device malposition can lead to complications and treatment failure.
Observation:
- An Ex-PRESS glaucoma drainage device dislocated into the anterior chamber.
- Excessive fibrosis formed at the implant site.
- The device was partially dislocated, impacting its function.
Findings:
- Successful retrieval of the dislocated Ex-PRESS device from the anterior chamber.
- Trabeculectomy performed at the superotemporal globe effectively relieved intraocular pressure.
- The patient's intraocular pressure was managed post-retrieval.
Implications:
- Trabeculectomy is a practical and effective surgical option for managing failed glaucoma drainage devices.
- This case highlights the importance of considering fibrosis in glaucoma surgery outcomes.
- Further research into managing complications of glaucoma drainage devices is warranted.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Ophthalmic Drug Delivery Systems
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

