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Seasonal effects on the nasolabial skin condition
1Department of Toxicology, Dermato-Cosmetology and Pharmacognosy, Vrije Universiteit Brussel (VUB), Brussels, Belgium. kdepaepe@vub.ac.be
Skin Pharmacology and Physiology
|October 4, 2008
Summary
Winter weather significantly impacts facial skin, increasing dryness and redness in the nasolabial area. This study reveals compromised skin barrier function during winter compared to autumn.
Area of Science:
- Dermatology
- Environmental Science
- Biophysics
Background:
- Seasonal changes, particularly cold weather, are known to affect skin barrier function.
- The nasolabial area is particularly sensitive to environmental factors due to its unique anatomical and physiological characteristics.
Purpose of the Study:
- To investigate the effects of seasonal changes (autumn vs. winter) on nasolabial skin condition in healthy women.
- To evaluate biophysical parameters and skin surface lipids in response to winter conditions.
Main Methods:
- 16 healthy female volunteers participated.
- Measurements included visual scoring (erythema, scaliness), transepidermal water loss (TEWL), skin hydration, skin pH, skin color, and desquamation.
- Skin surface lipids were analyzed using high-performance thin-layer chromatography.
Main Results:
- Nasolabial transepidermal water loss (TEWL) was significantly higher in winter than in autumn.
- Winter was associated with increased skin redness and scaliness, confirmed by colorimetry and squamometry.
- Analysis revealed significant differences in triglycerides and cholesterol esters, indicating a weakened hydrolipidic layer in winter.
Conclusions:
- Winter conditions negatively impact the nasolabial skin barrier, leading to increased TEWL and visible signs of dryness and irritation.
- The functional integrity of the skin's hydrolipidic layer is compromised during the winter season.
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