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01:26FDA Approved Drugs: Changes to Approved Drugs
Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...
01:28Drug Therapy
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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01:15Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
01:28Dosage Regimens: Designs and Approaches
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
01:25Pharmacokinetics: Drug–Drug Interactions
Drug interactions occur when the pharmacological effect of one drug is altered by another substance, either enhancing or diminishing its activity. The drug whose activity is altered is known as the object drug, and the substance causing the alteration is called the agent drug or the precipitant. The net effects of these interactions are mostly undesirable, leading to decreased effectiveness or increased adverse effects. In rare cases, interactions can be beneficial, such as the enhanced...
01:21Factors Affecting Drug Response: Overview
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
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Related Experiment Video
Updated: Jun 29, 2026
06:59
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
New medications and medication changes.
1Advanced Practice Nursing, College of Nursing, Kent State University, Kent, OH, USA.
Orthopedic Nursing
|October 4, 2008
Summary
Nurses educating patients on all medications, including orthopaedic drugs, should use the U.S. Food and Drug Administration (FDA) website for current drug information. Accessing FDA data ensures accurate patient education, reducing harm and anxiety.
Area of Science:
- Nursing
- Pharmacology
- Patient Education
Background:
- Nurses in orthopaedic settings educate patients on all prescribed medications, not solely those for the orthopaedic condition.
- Patient inquiries frequently involve new medications, dosage changes, or drug recalls from various sources.
- Accurate and up-to-date drug information is crucial for effective patient counseling.
Purpose of the Study:
- To highlight the U.S. Food and Drug Administration (FDA) website as a vital resource for nurses.
- To emphasize the importance of comprehensive medication education for patient safety.
- To provide examples of readily accessible drug information from the FDA.
Main Methods:
- Review of information available on the U.S. Food and Drug Administration (FDA) website.
Main Results:
- The FDA website offers timely information on recently approved drugs, new drug combinations, and new formulations of existing medications.
- The FDA provides critical drug alerts and safety warnings.
- Nurses can utilize this resource to address patient queries about medication updates and recalls.
Conclusions:
- Informed nurses utilizing the FDA website can provide accurate, comprehensive medication education.
- This practice helps mitigate potential patient harm associated with medication management.
- Empowering nurses with accessible drug information reduces patient stress and anxiety.