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Cutaneous sarcoidosis in Tunisia
A Khaled1, A Souissi, F Zeglaoui
1Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia. aida.khaled@rns.tn
Summary
This study inventories cutaneous sarcoidosis in Tunisia, finding diverse skin lesions and frequent extracutaneous involvement. Key features include a female predominance, high childhood case rates, and predominantly micronodular skin manifestations.
Area of Science:
- Dermatology
- Internal Medicine
- Epidemiology
Background:
- Sarcoidosis is a multisystem granulomatous disease with variable clinical presentations across ethnic and geographic groups.
- Local epidemiological data are crucial for understanding sarcoidosis patterns.
Purpose of the Study:
- To document the clinical presentation of cutaneous sarcoidosis in Tunisia.
- To identify specific clinico-epidemiological characteristics within the Tunisian population.
Main Methods:
- Retrospective review of medical records.
- Study conducted at a single academic teaching hospital over a 32-year period.
- Inclusion of both inpatient and outpatient cases diagnosed with sarcoidosis.
Main Results:
- 118 patients diagnosed with sarcoidosis (25 males, 93 females; mean age 39.5 years).
- Cutaneous sarcoidosis predominantly presented as micronodular lesions.
- Extracutaneous involvement was common (88% in lupus pernio cases), affecting eyes, bones, and lymph nodes; 30.1% had chest X-ray abnormalities.
Conclusions:
- Sarcoidosis in Tunisia presents with diverse cutaneous lesions and significant extracutaneous involvement.
- Distinctive features include a female predominance, a high frequency of childhood cases, and a prevalence of micronodular skin lesions.
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