Related Experiment Video
Updated: Jun 29, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
[Lower limb distal atherosclerotic gangrene--is high amputation always necessary?]
Abstract:
The results of treatment of patients with systemic atherosclerosis, complicated by foot and ankle soft tissue destruction. The majority of such patients are amenable to an incapacitating operation--a high femoral amputation. The results of arterial reconstructive measures do not always lead to a desirable effect, on the contrary, it can worsen the process and lead to a secondary amputation. The results of reconstructive treatment of 133 elderly and senile patients showed, that arterial reconstructive measures, amplified with necrectomy and minor amputation, allow to keep the limb and thus, the quality of life.
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