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Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Related Experiment Video

Updated: Jun 29, 2026

BioMEMS: Forging New Collaborations Between Biologists and Engineers
07:26

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

MEMS technology for nanobio research.

Dominique Collard1, Shoji Takeuchi, Hiroyuki Fujita

  • 1Center for International Research on MicroMechatronics, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan. collard@iis.u-tokyo.ac.jp

Drug Discovery Today
|October 7, 2008
PubMed
Summary
This summary is machine-generated.

Micro- and nanotechnology have advanced significantly over 20 years, focusing on micro/nanomechanisms and sensors. Emerging applications leverage this expertise for nanobiological topics and drug discovery, including MEMS tweezers and dynamic microarrays.

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Using Micro-Electro-Mechanical Systems (MEMS) to Develop Diagnostic Tools
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BioMEMS and Cellular Biology: Perspectives and Applications

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Last Updated: Jun 29, 2026

BioMEMS: Forging New Collaborations Between Biologists and Engineers
07:26

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Using Micro-Electro-Mechanical Systems (MEMS) to Develop Diagnostic Tools
16:05

Using Micro-Electro-Mechanical Systems (MEMS) to Develop Diagnostic Tools

Published on: October 1, 2007

BioMEMS and Cellular Biology: Perspectives and Applications
16:30

BioMEMS and Cellular Biology: Perspectives and Applications

Published on: October 1, 2007

Area of Science:

  • Micro- and nanotechnology
  • Nanobiotechnology

Background:

  • 20 years of research in micro- and nanotechnology.
  • Development of micro- and nanomechanisms, sensors, and actuators (10nm to 100µm).
  • Recent focus on transferring technology to nanobiological applications.

Purpose of the Study:

  • Review micro- and nanotechnology applications in nanobiology.
  • Highlight bio-oriented experiences with micromachined devices.
  • Foresee the contribution of these technologies to drug discovery.

Main Methods:

  • Review of micro- and nanotechnology research.
  • Description of MEMS tweezers for molecular handling.
  • Discussion of femto-L chambers for single molecular characterization.
  • Analysis of dynamic microarrays for cell positioning.

Main Results:

  • Demonstration of MEMS tweezers for direct molecular handling and characterization.
  • Capability for single molecular characterization in femto-L chambers.
  • Development of dynamic microarrays for precise cell positioning.

Conclusions:

  • Micro- and nanotechnology offer diverse applications in nanobiology.
  • Micromachined devices show significant potential for drug discovery.
  • Future contributions to drug discovery are anticipated through bio-oriented applications.