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Updated: Jun 29, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Non-invasive positive pressure ventilation for bilateral diaphragm paralysis after pediatric cardiac surgery
Lubica Kovacikova1, Dusan Dobos, Martin Zahorec
1Intensive Care Unit, Pediatric Cardiac Center, Bratislava, Slovakia. lkovacikova@yahoo.com
Insights
Two children experienced respiratory failure from diaphragm paralysis post-cardiac surgery. Non-invasive ventilation successfully managed their breathing, preventing intubation and allowing weaning after diaphragm function returned.
Area of Science:
- Pediatric Cardiology
- Respiratory Medicine
- Critical Care
Background:
- Cardiac surgery in children can lead to rare complications.
- Bilateral diaphragm paralysis is a potential post-operative respiratory complication.
Observation:
- Two pediatric patients developed respiratory failure post-cardiac surgery.
- This failure was attributed to bilateral diaphragm paralysis.
Findings:
- Non-invasive positive pressure ventilation (NIPPV) effectively managed respiratory distress.
- NIPPV improved gas exchange and avoided endotracheal intubation.
- Unilateral diaphragm recovery enabled successful weaning from NIPPV.
Implications:
- NIPPV is a viable treatment for pediatric respiratory failure due to diaphragm paralysis.
- Early intervention with NIPPV can prevent invasive ventilation in select cases.
- This approach offers a less invasive management strategy for post-cardiac surgery respiratory complications.
Abstract:
We present the case histories of two children having respiratory failure due to bilateral diaphragm paralysis after cardiac surgery. In both children non-invasive positive pressure ventilation alleviated respiratory distress, improved gas exchange, and prevented the need for endotracheal intubation. Following unilateral recovery of diaphragmatic function both children were successfully weaned from non-invasive positive pressure ventilation.
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