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Real-time Visualization and Analysis of Chondrocyte Injury Due to Mechanical Loading in Fully Intact Murine Cartilage Explants
08:42

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Published on: January 7, 2019

Phenotype of chondrocytes in osteoarthritis

Florenzo Iannone1, Giovanni Lapadula

  • 1Rheumatology Unit, DiMIMP, University of Bari, Bari, Italy. f.iannone@reumbari.uniba.it

Biorheology
|October 7, 2008
PubMed
Abstract

No abstract available in PubMed .

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

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