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Paediatric allergic reactions in the emergency department: a review
1Royal Hospital for Sick Children, 10/7 Wellington Street, Edinburgh EH75ED, UK. nicolamelville@hotmail.com
Insights
Acute allergic reactions in children are common, with nuts being a frequent trigger. Many young patients presenting to the pediatric emergency department (ED) with allergies do not receive adequate follow-up care.
Area of Science:
- Pediatric Emergency Medicine
- Allergy and Immunology
- Epidemiology
Background:
- Allergic diseases are a growing global health concern affecting a significant pediatric population.
- Research on pediatric allergic reactions, especially within emergency departments (EDs), is limited.
Purpose of the Study:
- To investigate the epidemiology of acute allergic reactions in children presenting to a pediatric ED.
- To analyze the treatment and outcomes of these allergic reactions.
Main Methods:
- A retrospective review of allergic reactions was conducted over a two-year period.
- Data were collected from a pediatric tertiary referral hospital ED with approximately 29,000 annual attendances.
Main Results:
- 237 pediatric patients experienced allergic reactions, with a median age of 46 months; 61% were male.
- The most common causes were nuts (23%), dairy (16.5%), and medications (10%). Oral exposure led to 58.6% of reactions, with skin symptoms being most prevalent.
- Only 5% received epinephrine, 19% were admitted, and 55% lacked formal follow-up.
Conclusions:
- Acute allergic reactions are more common in young boys and are frequently triggered by food allergens like nuts.
- Allergic reactions are a significant reason for pediatric ED visits.
- There are concerns regarding the insufficient follow-up care provided to children after experiencing allergic reactions.
Background:
Allergic diseases are increasing in incidence worldwide and large numbers of children are now affected by allergy. Few studies have examined allergic reactions in children, particularly in the emergency department (ED) setting.
Outcome Measures:
Primary--to describe the epidemiology of acute paediatric allergic reactions. Secondary--to describe the treatment and outcome of allergic reactions presenting to a paediatric ED.
Setting:
The ED of a paediatric tertiary referral hospital with approximately 29,000 ED attendances annually.
Methods:
A retrospective review of allergic reactions presenting to a paediatric ED over a 2-year period.
Main Results:
237 patients (61% male, median age 46 months) had reactions. 137/100,000 children attend the ED annually. The main identified causative agents were nuts (23%), dairy products (16.5%) and medication (10%). Oral contact was associated with 58.6% of reactions and dermatological symptoms were the most frequent presentation. Only 11(5%) received adrenaline (epinephrine). 46 (19%) were admitted. 55% of all patients received no formal follow-up.
Conclusions:
Acute allergic reactions affect boys more than girls and frequently occur at a young age. Food allergies, in particular to nuts, are a major cause of reactions. Allergy represents a frequent presentation to the paediatric ED. There remains a concern about the adequacy of follow-up.
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Allergies and anaphylaxis:...

