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Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

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Related Experiment Videos

Nutritional supplements for people being treated for active tuberculosis.

Katharine Abba1, Thambu D Sudarsanam, Liesl Grobler

  • 1International Health Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, Merseyside, UK, L3 5QA. K.abba@liverpool.ac.uk

The Cochrane Database of Systematic Reviews
|October 10, 2008
PubMed
Summary

Nutritional supplements, particularly high-energy options and combinations including zinc, may aid weight gain in tuberculosis patients. However, evidence for other nutrient combinations and impact on mortality or sputum conversion remains limited.

Related Experiment Videos

Area of Science:

  • Nutrition Science
  • Infectious Diseases
  • Public Health

Background:

  • Tuberculosis (TB) is a significant lung infection that can lead to nutritional deficiencies, potentially impairing immune function and delaying recovery.
  • Nutritional support may play a role in enhancing recovery for individuals undergoing tuberculosis treatment.

Purpose of the Study:

  • To evaluate the efficacy of oral nutritional supplements in promoting recovery among patients receiving antituberculous drug therapy for active tuberculosis.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) comparing oral nutritional supplements with no intervention, placebo, or dietary advice.
  • Searches conducted across multiple databases including Cochrane Infectious Disease Group Specialized Register, CENTRAL, MEDLINE, EMBASE, and LILACS up to June 2008.
  • Data extraction and risk of bias assessment performed independently by two authors; risk ratios and mean differences calculated with 95% confidence intervals.

Main Results:

  • Twelve RCTs involving 3393 participants were included.
  • High-energy supplements, multiple micronutrients plus zinc, and vitamin A plus zinc were associated with increased body weight.
  • No significant effect was observed on mortality or sputum test positivity rates at treatment end.

Conclusions:

  • Limited evidence suggests high-energy supplements and certain micronutrient combinations (including zinc) may promote weight gain in tuberculosis patients.
  • Insufficient evidence exists to determine the effects of other nutrient combinations on tuberculosis recovery.
  • Ongoing trials are expected to provide further insights for future updates.