Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...
Volumes of Solids of Revolution01:29

Volumes of Solids of Revolution

Volumes of irregularly shaped objects can be systematically determined using the concept of solids of revolution. This approach begins with a region defined by a curve in a two-dimensional plane. When this region is rotated about a fixed line, known as the axis of revolution, it generates a three-dimensional object with rotational symmetry. Such objects frequently arise in mathematical modeling, physics, and engineering applications.When the region being rotated lies directly against the axis...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Metallic Solids02:37

Metallic Solids

Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability. Many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protocol for detecting genome-wide introgressed genes and evaluating their functional legacy.

STAR protocols·2026
Same author

Psychosocial Factors Mediate the Relationship Between Olfactory Function and Cognitive Frailty in Older Adults: A Structural Equation Modelling.

Australasian journal on ageing·2026
Same author

Arabidopsis Circadian Clock Protein CCA1 Negatively Regulates the Calcium-Binding Protein CCaP1 to Modulate Dark-Responsive Stomatal Movement.

Plant, cell & environment·2026
Same author

Effectiveness of olfactory stimulation on improving cognitive function and behavioral and psychological symptoms of dementia in older adults with mild cognitive impairment or dementia: a systematic review and meta-analysis.

Aging & mental health·2026
Same author

Radiation-induced hepatic toxicity from radiotherapy plus immune checkpoint inhibitors with targeted therapy in HCC patients: a propensity score-matched study.

Radiation oncology (London, England)·2026
Same author

[Hepatotoxicity of cinnabar and its compound in mice after administration based on content of metal elements in vivo].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2026
Same journal

Donor-Acceptor Separation Augments Temperature Dependence of Kinetic Isotope Effects in NADH Model Hydride Transfer Reactions: Mimicking Enzyme versus Mutant Dynamics.

The journal of physical chemistry. B·2026
Same journal

Disordered Worm-Like Clusters in a Hexagonal Mesophase Former: Simulation and Thermodynamic Description.

The journal of physical chemistry. B·2026
Same journal

Comparative Biophysical Analysis of Healthy and Inflamed Intestinal Membrane Models Using Langmuir Monolayers.

The journal of physical chemistry. B·2026
Same journal

Phosphoserine Charge State Drives Ion Condensation and Spatial Polyamine Presentation in Multirepeat Silaffin.

The journal of physical chemistry. B·2026
Same journal

pH-Dependent Conformational Transition of the Glutamate-GABA Antiporter GadC Revealed by <sup>19</sup>F NMR.

The journal of physical chemistry. B·2026
Same journal

Hydrogen-Bond Network in Equimolar <i>N</i>-Methylacetamide-Water: Integrated Neutron Scattering, Molecular Dynamics, DFT-NBO-AIM, and Machine Learning Analysis.

The journal of physical chemistry. B·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2026

An In Vitro Organ Culture Model of the Murine Intervertebral Disc
08:03

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

Published on: April 11, 2017

Ordered packing of soft discoidal system.

Zhan-Wei Li1, Li-Jun Chen, Ying Zhao

  • 1Institute of Theoretical Chemistry, State Key Laboratory of Theoretical and Computational Chemistry, Jilin University, Changchun, China.

The Journal of Physical Chemistry. B
|October 14, 2008
PubMed
Summary
This summary is machine-generated.

Researchers used a novel simulation method to study how soft, disc-like particles pack. Anisotropic repulsive forces between these particles are sufficient to create ordered hexagonal columnar structures.

More Related Videos

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration
06:22

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration

Published on: July 8, 2021

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Related Experiment Videos

Last Updated: Jun 29, 2026

An In Vitro Organ Culture Model of the Murine Intervertebral Disc
08:03

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

Published on: April 11, 2017

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration
06:22

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration

Published on: July 8, 2021

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Area of Science:

  • Mesoscopic simulation methods
  • Soft matter physics
  • Materials science

Background:

  • Understanding particle packing is crucial for designing materials with specific properties.
  • Anisotropic particles exhibit unique self-assembly behaviors.
  • Soft repulsive interactions influence particle arrangement.

Purpose of the Study:

  • To investigate the ordered packing of anisotropic disklike particles with soft repulsion.
  • To explore the impact of particle shape, repulsion angular width, and strength on packing structures.
  • To demonstrate the efficacy of a modified dissipative particle dynamics method.

Main Methods:

  • Utilized a novel mesoscopic simulation technique.
  • Employed a modified anisotropic conservative force within dissipative particle dynamics.
  • Systematically varied particle shape, repulsion angular width, and repulsion strength.

Main Results:

  • Achieved ordered hexagonal columnar structures in simulations.
  • Identified key parameters influencing the formation of these structures.
  • Confirmed the sufficiency of anisotropic repulsive potential for ordered packing.

Conclusions:

  • Anisotropic repulsive forces between soft discoidal particles can spontaneously lead to ordered hexagonal columnar structures.
  • The mesoscopic simulation method provides insights into self-assembly of anisotropic soft matter.
  • Particle shape and repulsion characteristics are critical determinants of packing order.