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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

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Related Experiment Video

Updated: Jun 29, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

[Clinical advances in vascular calcification].

E D Fernández Giráldez1

  • 1Servicio de Nefrologia, Hospital Arnau de Vilanova (IRB Lleida), Spain.

Nefrologia : Publicacion Oficial De La Sociedad Espanola Nefrologia
|October 14, 2008
PubMed
Summary

Vascular calcification is a predictor of mortality in dialysis patients and the general population. While no treatments currently reverse it, sevelamer may slow progression in new hemodialysis patients.

Area of Science:

  • Nephrology
  • Cardiology
  • Vascular Biology

Background:

  • Vascular calcification is a significant clinical concern, impacting morbidity and mortality in both dialysis patients and the general population.
  • Arterial stiffness, closely related to vascular calcification, also serves as a prognostic indicator.
  • Markers like fetuin-A show associations with mortality, particularly in hemodialysis patients.

Purpose of the Study:

  • To review and synthesize current clinical knowledge on vascular calcification.
  • To address key questions regarding its measurement, significance, causes, and treatment.

Main Methods:

  • Systematic review of selected articles focusing on clinical utility and evidence.
  • Analysis of studies quantifying vascular calcification and arterial stiffness.

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A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
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A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

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  • Evaluation of research on etiological factors and therapeutic interventions.
  • Main Results:

    • Vascular calcification and arterial stiffness are established prognostic factors for morbidity and mortality.
    • Low bone turnover and diabetes are identified causes of cardiovascular disease and vascular calcification.
    • Sevelamer demonstrated potential in slowing vascular calcification progression and improving survival in new hemodialysis patients compared to calcium compounds.

    Conclusions:

    • Currently, no definitive treatments exist for the regression of vascular calcification.
    • Sevelamer may offer benefits in slowing progression and improving survival, especially in specific patient subgroups.
    • Further clinical studies are needed to confirm the efficacy of agents like paricalcitol and cinacalcet.