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Updated: Jun 29, 2026
07:54
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive sleep apnea syndrome is a systemic disease. Current evidence
Carlos Zamarron1, Vanesa García Paz, Alberto Riveiro
1Servicio de Neumología, Hospital Clínico Universitario, Santiago, Spain. carlos.zamarron.sanz@sergas.es
European Journal of Internal Medicine
|October 14, 2008
Summary
Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder with serious health consequences. Research suggests OSAS may increase the risk of developing metabolic syndrome and related cardiovascular issues, highlighting its systemic nature.
Area of Science:
- Sleep Medicine
- Cardiovascular Health
- Metabolic Disorders
Background:
- Obstructive sleep apnea syndrome (OSAS) is a prevalent sleep disorder causing breathing disruptions.
- OSAS is linked to daytime sleepiness, cognitive decline, metabolic issues, and reduced quality of life.
- Metabolic syndrome, a cluster of cardiovascular risk factors, is a growing public health concern.
Purpose of the Study:
- To explore the potential link between OSAS and the development of metabolic syndrome features.
- To investigate the increased risk of vascular events in OSAS patients.
- To understand OSAS as a systemic disease beyond a local respiratory abnormality.
Main Methods:
- Review of existing literature on OSAS and metabolic syndrome.
- Analysis of potential mechanisms linking OSAS to metabolic and cardiovascular alterations.
- Examination of biomarkers associated with systemic consequences in OSAS patients.
Main Results:
- OSAS presence may elevate the risk of developing metabolic syndrome components.
- OSAS patients exhibit a higher risk for vascular events, a major cause of mortality.
- Systemic inflammation, autonomic nervous system changes, and coagulation imbalances are implicated in OSAS.
Conclusions:
- OSAS is associated with significant endocrine-metabolic and cardiovascular alterations.
- Biomarker evidence supports OSAS as a systemic disease.
- OSAS management is crucial for mitigating broader health risks.
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