Related Experiment Video
Updated: Jun 29, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
[Systemic lupus erythematosus and pregnancy]
Véronique Le Guern1, Emmanuelle Pannier, François Goffinet
1Service de Médecine Interne, Hôpital Cochin, Université Paris Descartes, Paris, France. veronique.le-guern@cch.aphp.fr
Abstract:
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that predominantly affects women of childbearing age. Prognosis of SLE pregnancy has dramatically improved with the advent in therapeutic management of SLE and in the obstetric care. Consequently, pregnancy is possible in SLE patients when the disease is inactive for at least 6 months. Because of the risk of lupus flare and obstetrical complications (fetal loss, preterm birth, intrauterine growth retardation, preeclampsia), a multidisciplinary approach, associating medical and obstetrical teams, is required. Corticosteroids, hydroxychloroquine and azathioprine are safe in pregnancy and should be kept when necessary.
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Hormonal Regulation
Rh Blood Group
Diabetes Mellitus: Type 2 and Gestational
Teratogenicity