Values for macular perimetry using the MP-1 microperimeter in normal subjects

Area of Science:

• Ophthalmology
• Neuroscience
• Gerontology

Background:

• Macular sensitivity and fixation stability are crucial for visual function.
• Age-related changes in these parameters are not fully characterized in healthy populations.

Purpose of the Study:

• To establish normative values for macular light sensitivity and fixation stability in healthy subjects.
• To evaluate the MP-1 microperimeter's utility in measuring these parameters.

Main Methods:

• Prospective study of 37 healthy subjects (19-71 years).
• Full-threshold microperimetry using the MP-1 across 16 points in the central 12 degrees of the macula.
• Simultaneous recording of fixation stability during microperimetry, with linear regression analysis for age-related changes.

Main Results:

• Mean macular sensitivity was 18.33 dB, showing a slight age-related decline (0.019-0.028 dB/year).
• Mean fixation stability was 86% (2 degrees) and 96% (4 degrees), also declining with age (0.344% and 0.122%/year, respectively).
• No significant differences in sensitivity or fixation were found based on sex or race.

Conclusions:

• The MP-1 microperimeter is a reliable tool for assessing macular sensitivity.
• A linear decline in light sensitivity and fixation stability with increasing age is evident in healthy individuals.