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Endogenous opiates and behavior: 2007

Richard J Bodnar1

  • 1Department of Psychology and Neuropsychology Doctoral Sub-Program, Queens College, City University of New York, 65-30 Kissena Blvd.,Flushing, NY 11367, United States. richard.bodnar@qc.cuny.edu

Peptides
|October 15, 2008
PubMed

Insights

This review covers 2007 research on the endogenous opioid system, detailing how manipulating opioid peptides and receptors impacts behavior. It explores roles in pain, stress, addiction, and more.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Behavioral Science

Background:

  • The endogenous opioid system modulates numerous physiological and behavioral processes.
  • Annual reviews are crucial for synthesizing research on this complex system.

Purpose of the Study:

  • To summarize research published in 2007 on the behavioral effects of endogenous opioid system manipulation.
  • To provide an overview of studies investigating opioid peptides, receptors, agonists, and antagonists.

Main Methods:

  • Review of scientific literature published in 2007.
  • Analysis of studies involving molecular, pharmacological, and genetic manipulation of opioid system components.
  • Synthesis of findings related to behavioral outcomes.

Main Results:

  • Behavioral effects were examined across diverse areas including pain, stress, learning, addiction, and mood.
  • Research explored the neurochemical localization and molecular-biochemical effects of endogenous opioids and their receptors.
  • Studies investigated the roles of the opioid system in functions such as feeding, reproduction, and neurological disorders.

Conclusions:

  • The endogenous opioid system significantly influences a wide spectrum of behaviors and physiological functions.
  • Continued research is vital for understanding the intricate roles of opioid peptides and receptors.
  • This review highlights the broad impact of opioid system research on various scientific disciplines.

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