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Updated: Jun 29, 2026

Eye Tracking Young Children with Autism
Published on: March 27, 2012
Screening strategies for autism spectrum disorders in pediatric primary care
Jennifer A Pinto-Martin1, Lisa M Young, David S Mandell
1Biobehavioral and Health Sciences Division, University of Pennsylvania School of Nursing, Philadelphia, PA 19104, USA. pinto@nursing.upenn.edu
Insights
Using a general developmental screening tool first misses many children at risk for autism spectrum disorder (ASD). An autism-specific screening tool for all children is recommended alongside standard developmental screening.
Area of Science:
- Developmental Pediatrics
- Child Psychology
- Autism Spectrum Disorder Research
Background:
- Two strategies exist for early autism spectrum disorder (ASD) identification: a two-step approach using general then ASD-specific screening, or an ASD-specific tool for all children.
- The comparative effectiveness of these early identification strategies has not been previously examined.
Purpose of the Study:
- This study aimed to compare the yield of children identified at risk for ASD between 18 and 30 months of age using a general developmental screening tool versus an autism-specific screening tool.
Main Methods:
- The Parents' Evaluation of Developmental Status (PEDS) served as the general screening tool.
- The Modified Checklist for Autism in Toddlers (M-CHAT) was employed as the autism-specific screening tool.
- Both tools were administered concurrently to 152 children.
Main Results:
- When PEDS identified developmental concerns (n=38), 16% also screened positive for ASD on the M-CHAT.
- When PEDS did not identify developmental concerns (n=114), 14% still screened positive for ASD on the M-CHAT (p = .79).
- The PEDS failed to identify the majority of children who screened positive for ASD on the M-CHAT.
Conclusions:
- The PEDS and M-CHAT appear to assess different developmental domains.
- Findings suggest that an ASD-specific tool is necessary for all children.
- Routine developmental screening should incorporate an autism-specific tool for comprehensive early identification of ASD.
Background:
Two strategies have been proposed for early identification of children with autism spectrum disorders (ASD): (1) using a general screening tool followed by an ASD-specific screening tool for those who screen positive on the former or (2) using an ASD-specific tool for all children. The relative yield of these two strategies has not been examined.
Objectives:
This study compared the number of children identified at risk for ASD at their well child visits between the ages of 18 and 30 months using a general developmental screening tool and an autism-specific screening tool.
Methods:
The Parents' Evaluation of Developmental Status (PEDS) was used as the general developmental screening tool and the Modified Checklist for Autism in Toddlers (M-CHAT) was used as the autism-specific tool. These tools were administered concurrently to 152 children.
Results:
Cross tabulations and chi tests were used to determine the utility of the PEDS as the first step of a two-part screen for ASD. Of those who screened positive for developmental concerns on the PEDS (n = 38), 16% screened positive for ASD on the M-CHAT; of those who did not screen positive for developmental concerns on the PEDS (n = 114), 14% screened positive for ASD on the M-CHAT (p = .79).
Conclusion:
The PEDS missed the majority of children who screened positive for ASD on the M-CHAT, suggesting that these two tools tap into very different domains of developmental concerns. The findings support the use of an ASD-specific tool for all children in conjunction with regular standardized developmental screening.
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