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Related Concept Videos

Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

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Related Experiment Video

Updated: Jun 29, 2026

Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells
08:44

Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells

Published on: June 22, 2013

Stem cells in urology.

Tamer Aboushwareb1, Anthony Atala

  • 1Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

Nature Clinical Practice. Urology
|October 15, 2008
PubMed
Summary
This summary is machine-generated.

Stem cell research offers a promising solution for organ shortages in transplantation. Advances in regenerative medicine and tissue engineering are paving the way for new urologic therapies.

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A Novel Clinical Grade Isolation Method for Human Kidney Perivascular Stromal Cells
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A Novel Clinical Grade Isolation Method for Human Kidney Perivascular Stromal Cells

Published on: August 7, 2017

Related Experiment Videos

Last Updated: Jun 29, 2026

Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells
08:44

Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells

Published on: June 22, 2013

A Novel Clinical Grade Isolation Method for Human Kidney Perivascular Stromal Cells
09:05

A Novel Clinical Grade Isolation Method for Human Kidney Perivascular Stromal Cells

Published on: August 7, 2017

Area of Science:

  • Regenerative Medicine
  • Urology
  • Stem Cell Biology

Background:

  • Organ transplantation faces donor shortages, driving research into stem cells for therapeutic applications.
  • Ethical concerns surrounding embryonic stem cells have shifted focus to adult, amniotic, and placental stem cells.
  • Novel laboratory techniques like somatic cell nuclear transfer and cell reprogramming are advancing stem cell generation.

Purpose of the Study:

  • To explore the potential of stem cells in regenerative medicine for urologic applications.
  • To review advancements in tissue engineering for urologic disorders.
  • To assess the future prospects of cell therapy in urology.

Main Methods:

  • Investigated stem cell sources beyond embryonic cells, including adult and alternative sources.
  • Examined novel techniques for in-vitro stem cell generation, such as somatic cell nuclear transfer and reprogramming.
  • Reviewed tissue engineering strategies applied to urologic tissues.

Main Results:

  • Regenerative techniques for bladder tissue have been successfully translated to clinical practice.
  • Significant progress is being made in the regeneration of kidney and urethral tissues.
  • Cell therapy for conditions like incontinence and infertility shows future potential.

Conclusions:

  • Regenerative medicine and tissue engineering hold immense promise for treating urologic disorders.
  • Stem cell-based therapies are expected to become mainstream treatment options in urology.
  • Continued research and development in these fields are crucial for clinical translation.