Prevalence of coronary artery disease and preoperative assessment in patients with valvopathy
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Updated: Jun 29, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Roney Orismar Sampaio1, Vívian Masutti Jonke, João L Falcão
1Departamento de Valvopatias, Instituto do Coração, Brasil. val_roney@incor.usp.br
Insights
Coronary artery disease (CAD) prevalence is low in patients undergoing valve surgery. Routine preoperative coronary angiography in valvopathy patients over 35 may need reevaluation, especially for those under 50 with risk factors.
Area of Science:
- Cardiology
- Vascular Medicine
- Cardiac Surgery
Background:
- Preoperative coronary angiography is standard for valvopathy patients over 35.
- The prevalence of obstructive coronary artery disease (CAD) in this demographic is not well-established.
Purpose of the Study:
- To determine the prevalence of CAD in Brazilian patients undergoing valve surgery.
- To identify risk factors associated with CAD in this patient group.
Main Methods:
- Coronary angiography was performed on 3,736 patients scheduled for valve surgery.
- Data on CAD prevalence and associated risk factors were collected and analyzed.
Main Results:
- A 3.42% prevalence of CAD was found in association with valvopathy (121 patients).
- Aortic valvopathy was the most common type associated with CAD.
- Most patients with CAD (95.7%) were over 50; younger patients (<50) with CAD had risk factors.
Conclusions:
- The prevalence of CAD in candidates for valve surgery is low.
- Aortic valvopathy is frequently linked with CAD in these patients.
- The established age threshold for routine preoperative coronary angiography in valvopathy patients warrants reassessment.
Background:
Coronary angiography has been indicated in the preoperative phase for patients with valvopathy over 35 years of age. However, the actual prevalence of obstructive coronary artery disease (CAD) in this population has been little studied.
Objective:
To assess the prevalence of and the risk factors for CAD in candidates for valve surgery in Brazil.
Methods:
Coronary angiography was performed in 3,736 patients who were candidates for valve surgery; prevalence of and risk factors for CAD associated with valvopathy were assessed.
Results:
CAD was associated with valvopathy in 121 patients (prevalence of 3.42%). In 79 patients (68.1%), CAD was diagnosed by means of preoperative coronary angiography. Of these 79 patients, 50 (63.3%) had isolated aortic valvopathy or aortic valvopathy associated with mitral valvopathy. Smoking habit was observed in 54 patients (68.3%), hypertension in four (43%), family history in 24 (30.3%), diabetes mellitus in 15 (18.9%), and obesity in eight (10.1%). Of the 121 patients, 95.7% were over 50 years of age. Only five (4.3% of the patients with CAD) were below 50 years of age, and all of them had at least one risk factor for CAD.
Conclusion:
CAD prevalence was low in the patients studied. Aortic valvopathy was the most frequent valvopathy associated with CAD, and most patients were over 50 years of age. The ideal age for routine preoperative coronary angiography in patients with valvopathy should be reassessed.
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