Related Experiment Video
Updated: Jun 29, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Novel diaryl or heterocyclic sulfonamides as antimitotic agents
Laixing Hu1, Zhuo-rong Li, Jian-dong Jiang
1Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30303, USA.
Abstract:
The sulfonamides constitute an important class of drugs, which display a variety of activities including antibacterial, anti-carbonic anhydrase, diuretic, hypoglycemic and antithyroid effectiveness. A number of sulfonamides have been reported to be potent anticancer agents, which interact with a wide range of different cellular targets. Among these interesting sulfonamides, the diaryl or heterocyclic sulfonamides have recently emerged as an important class of antimitotic agents against different types of cancer, including multidrug resistant tumors. This review summarizes the recent advances of the diaryl or heterocyclic sulfonamides as novel antimitotic agents.
Related Concept Videos
Anthelminthic Agents
Antifungal Agents
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Drugs that Destabilize Microtubules
Antiprotozoal Agents
Antiviral Nucleoside Inhibitors
