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[The toxicity of surface-active substances for emulsifying perfluorocarbon compounds as components of blood
1Militärmedizinische Akademie, Bad Saarow.
Die Pharmazie
|April 1, 1991
Abstract:
Perfluorocarbons are insoluble in water. For being used as oxygen carriers in blood substitutes they therefore have to be emulsified. Using surfactants in the living organism a compromise on the emulsifying effect and toxicity is to be made, since good emulsifiers do also affect biological membranes. The influence of molecule parameters of surfactants on toxicity was studied in this paper.