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Plexiform granular cell odontogenic tumor: unicystic variant
1Department of Oral Pathology & Oral Medicine, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
Oral Surgery, Oral Medicine, and Oral Pathology
|July 1, 1991
Summary
Plexiform granular cell odontogenic tumor (PGCOT) is a rare mandibular neoplasm. This report details a unicystic variant in a middle-aged woman, differing from previously described solid forms in elderly men.
Area of Science:
- Oral pathology
- Odontogenic tumors
- Histopathology
Background:
- Plexiform granular cell odontogenic tumor (PGCOT) is a recently described entity.
- Its key feature is a monophasic plexiform pattern of granular cells.
- Granular cell ameloblastoma is a primary differential diagnosis.
Observation:
- This report presents a unicystic variant of PGCOT.
- The lesion occurred in a middle-aged woman.
- This contrasts with two prior cases presenting as solid tumors in elderly men.
Findings:
- The unicystic variant exhibits the characteristic plexiform pattern of granular cells.
- Histopathological analysis confirms the diagnosis.
- Clinical presentation and imaging may aid in differentiating variants.
Implications:
- This case expands the known clinicopathologic spectrum of PGCOT.
- Recognizing unicystic variants is crucial for accurate diagnosis and treatment.
- Further research may elucidate the pathogenesis and behavior of different PGCOT variants.