Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply to "Clinical pathway implications of bilateral hypoglossal nerve stimulation for PAP-intolerant OSA".

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2026
Same author

The effect of tongue strength and endurance in patients with obstructive sleep apnea.

Sleep & breathing = Schlaf & Atmung·2026
Same author

2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association·2025
Same author

Bilateral hypoglossal nerve stimulation for obstructive sleep apnea: a nonrandomized clinical trial.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2025
Same author

Modified uvulopalatopharyngoplasty in modern obstructive sleep apnea treatment: a narrative review.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2025
Same author

Home sleep study nasal airflow patterns and epiglottic collapse during drug induced sleep endoscopy.

Sleep & breathing = Schlaf & Atmung·2025

Related Experiment Video

Updated: Jun 28, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Palate implants for obstructive sleep apnea: multi-institution, randomized, placebo-controlled study.

David L Steward1, Todd C Huntley, B Tucker Woodson

  • 1Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA. David.Steward@uc.edu

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|October 17, 2008
PubMed
Summary
This summary is machine-generated.

Pillar palate implants showed some efficacy for mild to moderate obstructive sleep apnea (OSA), improving certain measures over placebo. However, overall effectiveness was limited, indicating a need for further research in OSA treatment.

More Related Videos

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
05:54

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla

Published on: October 18, 2021

Related Experiment Videos

Last Updated: Jun 28, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
05:54

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla

Published on: October 18, 2021

Area of Science:

  • Sleep Medicine
  • Otolaryngology
  • Medical Devices

Background:

  • Obstructive sleep apnea (OSA) is a common condition affecting sleep quality and health.
  • Retropalatal obstruction is a key factor in mild to moderate OSA.
  • Current treatments have varying efficacy and patient adherence.

Purpose of the Study:

  • To evaluate the efficacy of Pillar palate implants in treating mild to moderate obstructive sleep apnea (OSA).
  • To compare implant treatment against a placebo in a randomized, double-blind study.

Main Methods:

  • A multi-institution, randomized, double-blind, placebo-controlled study.
  • 100 patients with mild to moderate OSA and suspected retropalatal obstruction were enrolled.
  • Patients received either three palatal implants or a sham placebo.

Main Results:

  • The implant group showed a less pronounced increase in the apnea-hypopnea index (AHI) compared to placebo.
  • A clinically meaningful reduction in AHI was more frequent in the implant group (26% vs. 10%).
  • Significant improvements were observed in lowest oxyhemoglobin saturation and the Functional Outcomes of Sleep Questionnaire, but not in the Epworth Sleepiness Score. Minor side effects like implant extrusion occurred in 4% of patients.

Conclusions:

  • Pillar palate implants demonstrated efficacy over placebo for specific outcome measures in mild to moderate OSA.
  • The treatment showed minimal morbidity but limited overall effectiveness.
  • Further investigation is warranted to fully understand the role of palate implants in OSA management.