Management of early-invasive high-grade transitional cell carcinoma of the bladder

The decision in favor or against an early cystectomy in patients with initial pT1G3 urothelial carcinoma of the bladder (UCBC) is challenging. In the present review the authors dwell on the key issues in the controversial discussion about optimal management of so called ''early invasive'' UCBC. The quality of transurethral resection of the bladder tumor (TURBT) as diagnostic and therapeutic method plays an important role. Histopathological assessment delivers crucial risk factors for stratification. Last but not least life quality under different therapeutic regimes should be comprised in the decision process.