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[Endoscopic augmentation of neurogenic bladder with botulinum-A toxin in children]

Paweł Kroll1, Andrzej Jankowski, Jacek Zachwieja

  • 1Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Katedra i Klinika Chirurgii, Traumatologii i Urologii Dzieciecej. pakroll@poczta.onet.pl

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|October 18, 2008
PubMed

Insights

Botulinum-A toxin injections are effective for treating neurogenic bladder overactivity in children. This endoscopic treatment improved bladder volume in most young patients with minimal side effects.

Area of Science:

  • Pediatric Urology
  • Neurology
  • Gastroenterology

Context:

  • Neurogenic bladder overactivity affects children, leading to significant voiding dysfunction.
  • Conservative treatments may be insufficient for managing this condition.

Purpose:

  • To evaluate the efficacy and safety of endoscopic intradetrusor injections of botulinum-A toxin (BTX) in pediatric patients.
  • To assess changes in bladder volume and urodynamic parameters post-treatment.

Summary:

  • Twenty-five children aged 3-7 years with neurogenic bladder overactivity underwent endoscopic BTX injections.
  • Post-procedure, 18 patients showed increased bladder volume, while 5 experienced a decrease.
  • No major adverse events were reported following BTX administration.

Impact:

  • Endoscopic botulinum-A toxin injections represent a viable treatment option for pediatric neurogenic bladder overactivity.
  • The procedure demonstrates a favorable safety profile and potential for improving bladder capacity in affected children.
Abstract

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