Related Experiment Video

Updated: Jun 28, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
06:37

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

[Malformations of urinary system in our series of children--treatment approaches]

Beata Bieniaś1, Halina Borzecka, Anna Wieczorkiewicz-Płaza

  • 1Klinika Nefrologii Dzieciecej UM w Lublinie. ped_nefr@dsk.lublin.pl

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|October 18, 2008
PubMed

Insights

Pediatric urinary system malformations were analyzed in 557 children. Pharmacologic treatment for most vesicoureteral reflux cases led to complete recovery, reducing surgical needs.

Area of Science:

  • Pediatric Nephrology
  • Urology

Context:

  • Retrospective analysis of 557 children (aged 1-18) hospitalized between 2000-2007.
  • Focus on malformations of the urinary system in a pediatric cohort.

Purpose:

  • To analyze treatment approaches for pediatric urinary system malformations.
  • Evaluate the effectiveness of different treatment strategies for common conditions like vesicoureteral reflux and obstructions.

Summary:

  • Common malformations included vesicoureteral reflux (269), ureteral obstruction (102), urethral obstruction (91), and renal duplication (83).
  • 332 children required surgery, but the majority of vesicoureteral reflux cases (113) achieved complete recovery with an average of 18 months of pharmacologic treatment.
  • Multiple urinary system malformations were diagnosed in 26 children.

Impact:

  • Highlights the efficacy of conservative pharmacologic management for vesicoureteral reflux in children.
  • Provides insights into surgical and non-surgical treatment outcomes for various pediatric urogenital malformations.
  • Informs clinical decision-making for managing complex urinary system abnormalities in pediatric patients.

More Related Videos

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection06:05

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

Surgical Management of Meatal Stenosis with Meatoplasty04:53

Surgical Management of Meatal Stenosis with Meatoplasty

Published on: November 30, 2010

Related Concept Videos

Disorders of the Urinary System01:20

Disorders of the Urinary System

The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...