First basic performance evaluation of the XE-2100 haematology analyser

Area of Science:

• Clinical laboratory diagnostics
• Haematology automation

Background:

• The XE-2100 is a novel haematology analyser.
• It offers complete blood counts, leukocyte differentials, reticulocyte analysis, and nucleated red blood cell (NRBC) quantification.

Purpose of the Study:

• To evaluate the basic performance of the XE-2100 haematology analyser.
• Assessment included reproducibility, carryover, storage stability, and accuracy.

Main Methods:

• Evaluation used routinely obtained blood specimens treated with ethylenediaminetetraacetic acid-2K.
• Performance metrics assessed included reproducibility, carryover, storage stability (4°C and room temperature), and accuracy.
• Comparisons were made against the SE-9000 haematology analyser and manual methods.

Main Results:

• Good reproducibility and minimal carryover were observed.
• Accurate measurements were maintained for up to 48 hours of storage.
• High correlation (r > 0.9) was found for complete blood counts and leukocyte differentials (neutrophils, lymphocytes, eosinophils) compared to the SE-9000 and manual counts.
• Nucleated red blood cell (NRBC) and reticulocyte counts demonstrated satisfactory precision and accuracy.
• Differential counts for bone marrow aspirates correlated well with manual differentials.

Conclusions:

• The XE-2100 haematology analyser exhibits excellent performance characteristics.
• The instrument is capable of providing reliable and accurate data for clinical laboratories.
• Its comprehensive capabilities make it a valuable tool for haematological analysis.