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Updated: Jun 28, 2026
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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive sleep apnea in ischemic stroke patients
Aliye Tosun1, Ouz Köktürk, Gülçin Kaymak Karata
1Department of Physical Medicine and Rehabilitation, Kirikkale University Faculty of Medicine, Kirikkale, Turkey.
Clinics (Sao Paulo, Brazil)
|October 18, 2008
Summary
Obstructive sleep apnea affects over 70% of ischemic stroke patients. Early diagnosis and treatment with nasal continuous positive airway pressure (CPAP) are crucial for secondary stroke prevention.
Area of Science:
- Neurology
- Sleep Medicine
- Cardiology
Background:
- Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated episodes of upper airway collapse during sleep.
- Ischemic stroke is a leading cause of disability and mortality worldwide.
- The relationship between OSA and ischemic stroke, particularly regarding OSA prevalence and treatment efficacy, requires further investigation.
Purpose of the Study:
- To determine the prevalence of obstructive sleep apnea (OSA) in patients who have experienced an ischemic stroke.
- To assess the effectiveness of nasal continuous positive airway pressure (CPAP) therapy in managing OSA in this patient population.
Main Methods:
- Overnight polysomnography was conducted using a computerized system for 19 ischemic stroke patients.
- Obstructive sleep apnea was diagnosed based on an apnea-hypopnea index (AHI) of 5 or higher.
- Continuous positive airway pressure (CPAP) levels were determined via an all-night CPAP determination study and attended titration with an auto-titrating device.
Main Results:
- The prevalence of obstructive sleep apnea (OSA) among ischemic stroke patients was found to be 73.7%.
- Patients with OSA exhibited significantly lower minimum oxygen saturation (SaO2) and longer durations of wakefulness and stage 1 sleep.
- In two severe OSA cases, CPAP treatment led to a reduced AHI, increased mean and minimum SaO2, and altered sleep architecture.
Conclusions:
- The high prevalence of obstructive sleep apnea (OSA) in ischemic stroke patients underscores its clinical significance.
- Routine screening for OSA in stroke patients within rehabilitation units is recommended.
- Initiating early treatment for OSA is suggested as a critical component of secondary stroke prevention strategies.
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