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Extra-cardiac findings at cardiac CT: experience with 1,764 patients
Jay Koonce1, Joseph U Schoepf, Shaun A Nguyen
1Department of Radiology, Medical University of South Carolina, Charleston, SC 29425, USA.
Insights
Incidental extra-cardiac findings (ECF) are common in cardiac CT scans, particularly with coronary artery CT angiography and bypass graft studies. These findings impact patient management, with 18% requiring follow-up.
Area of Science:
- Radiology
- Cardiovascular Imaging
- Medical Diagnostics
Background:
- Incidental extra-cardiac findings (ECF) are frequently discovered during cardiac CT examinations.
- Understanding the prevalence and clinical significance of ECFs based on CT indication is crucial for patient management.
Purpose of the Study:
- To investigate the incidence and characteristics of incidental extra-cardiac findings (ECF) detected during cardiac CT.
- To compare the frequency of ECFs across different cardiac CT indications: calcium scoring (CS), coronary CT angiography (CTA), pulmonary vein stenosis (PVS), and coronary artery bypass graft (CABG) imaging.
Main Methods:
- Retrospective review of 1,764 cardiac CT reports (January 2004 - December 2006).
- ECFs were categorized by examination type, anatomical location, and clinical significance.
- Statistical comparisons were performed between different cardiac CT indications.
Main Results:
- A total of 507 ECFs were identified in 441 patients (25.0%).
- Clinically important ECFs requiring follow-up were found in 18.4% of patients.
- ECFs were significantly more frequent in coronary artery bypass graft (CABG) studies (38.6%) and coronary CT angiography (CTA) (26.6%) compared to calcium scoring (CS) (17.1%).
- Statistically significant differences (p < 0.05) were observed between CABG and other indications, and between CTA and CS for both incidental and clinically important findings.
Conclusions:
- Incidental extra-cardiac findings are common in cardiac CT, with a substantial proportion being clinically significant.
- Coronary artery bypass graft imaging and coronary CT angiography are associated with a higher incidence of ECFs compared to calcium scoring.
- These findings underscore the importance of careful review of cardiac CT studies for ECFs to optimize patient care.
Abstract:
To investigate incidental extra-cardiac findings (ECF) at cardiac CT based on indication and impact on patient management. We retrospectively reviewed the reports of 1,764 patients who underwent a cardiac CT study between January 1, 2004 and December 31, 2006, including 463 calcium scorings (CS), 737 coronary CT angiograms (CTA), 341 pulmonary vein stenoses (PVS), and 223 bypass grafts (CABG). ECFs were categorized by type of examination, anatomical location and clinical significance. Comparisons were made between examination types to determine if incidental findings varied by indication. There were 507 ECFs with at least one ECF in 441 patients (25.0%). By examination, there was at least 1 ECF in 79/463 CS studies (17.1%), 196/737 CTAs (26.6%), 80/341 PVSs (23.4%) and 86/223 CABGs (38.6%). In 325 patients (18.4%), the findings were considered clinically important and occurred in 60/463 (12.9%) CSs, 149/737 (20.2%) CTAs, 56/341 (16.4%) PVSs and 60/223 (26.9%) CABGs. Differences between CABG and other indications and CTA vs. CS for incidental and clinically important findings were statistically significant (p < 0.05). Extra-cardiac findings requiring follow-up occur in 18% of patients and are significantly more frequent in coronary artery CTA and coronary artery bypass studies than in calcium scoring studies.
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