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Interferon-alpha controls IL-17 expression in vitro and in vivo

Alexander R Moschen1, Sabine Geiger, Ingomar Krehan

  • 1Christian Doppler Research Laboratory for Gut Inflammation and Clinical Division of Gastroenterology and Hepatology, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.

Immunobiology
|October 18, 2008
PubMed
Summary

Type I interferons like interferon alpha (IFNalpha) suppress interleukin-17 (IL-17) production and Th17 cell differentiation. This finding suggests a potential mechanism for IFNalpha in treating inflammatory diseases.

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