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Bite force and pattern measurements for dental pain assessment in the rat

Junad Khan¹, Rafael Benoliel, Uri Herzberg

¹Division of Orofacial Pain, Suzan and Robert Carmel Endowed Chair in Algesiology, Department of Diagnostic Sciences, UMDNJ, New Jersey Dental School, 110 Bergen Street, Newark, NJ 07103, USA.

Neuroscience Letters

|October 18, 2008

Abstract:

We present simple method to assess dental pain in the awake rat. Using a sensitive strain gauge we examined changes in bite strength and bite pattern in rats following dental injury. Rats with dental injury displayed a significant reduction in mean peak bite strength and an altered bite cluster pattern. Both changes in the dental injury rats were reversed by an analgesic dose of morphine, and this could be reversed with naloxone. These changes were not observed in naive control animals. This simple method significantly improves our ability to evaluate dental pain syndromes.

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