Related Experiment Video
Updated: Jun 28, 2026

07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Monitoring glaucoma progression
1Department of Ophthalmology, Santa Maria della Misericordia Hospital, Udine (Italy), Piazzale S. Maria della Misericordia, 15 33100 Udine, Italy. brusini@libero.it
Progress in Brain Research
|October 22, 2008
Summary
Monitoring chronic open-angle glaucoma progression requires assessing both structural and functional damage. Reliable progression detection ensures timely clinical management and patient care.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Medical Imaging
Background:
- Chronic open-angle glaucoma (COAG) management necessitates vigilant progression monitoring.
- Assessing both structural and functional damage is crucial for a comprehensive evaluation.
Purpose of the Study:
- To outline essential methods for monitoring glaucoma progression.
- To emphasize the importance of integrating structural and functional assessments.
Main Methods:
- Structural damage evaluation using low-tech (slit lamp biomicroscopy) and high-tech (HRT, OCT, GDx) imaging.
- Functional damage assessment via standard automated perimetry (SAP).
- Discussed SAP progression analysis approaches: clinical judgment, defect classification, trend analysis, and event analysis.
Main Results:
- High-tech imaging offers more objective and standardized structural damage analysis.
- Standard automated perimetry (SAP) remains the gold standard for functional damage detection.
- Statistical programs aid ophthalmologists in assessing progression.
Conclusions:
- Clinically relevant glaucoma progression is defined by statistically significant, reproducible changes.
- Integrated structural and functional monitoring is key for reliable COAG management.
- Accurate progression assessment guides effective patient care strategies.
Related Concept Videos
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
